Console says waiting for connection / message: There was a problem sending data to the laser. The machine may be busy or paused

When I hit start, Lightburn message says :
There was a problem sending data to the laser.

The machine may be busy or paused.
console says:
Waiting for connection…

Waiting for connection…

File imported in 49 milliseconds

Waiting for connection…

Port failed to open - already in use?

Waiting for connection…

Port failed to open - already in use?

PLEASE HELP!!!
I don’t know how to fix.
Thanks

Few things to quickly ask about.

Have you installed the CH340/CH341 driver? (first step)

Can you see the USB serial port connection in LightBurn Laser window?
Use the Bottom middle button in that window to attempt to find it.

This video is excellent. Jump ahead to 8:17 and enjoy the guided tour.
Thanks everyone for putting this together:

I apologize


it took me a couple of days to get back to you. We have been out of pocket so here I tried everything you listed below. I watch the video twice and followed along exactly as it said and say picture of what it shows me after I followed all the instructions. It still says waiting for connection Port failed.
I’m not for sure what I need to do next to make this work?. I truly appreciate any help you can give me. And FYI, laser box works fine it’s just the light burn.
Katie Turner

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