One of the emerging possibilities is that LightBurn may have trouble with the xTool D1 controller Mounting itself as a drive. It was discovered on other engravers, but the processor is similar if not identical.
On the windows 10 PC, check out the video in the last post of this thread:
Please follow the 2-3 steps and test to see if that is happening and if this approach allows LightBurn to operate the laser without losing connection.
Which xTool D1 Firmware are you currently running?
You can see the exact version number and copy it from the Console window in LightBurn and paste it into a reply here.