Can I cut Severe Weather 15/32-in x 4-ft x 8-ft CDX Pressure Treated Southern Yellow Pine Plywood Sheathing on laser to use for small outdoor sign if painted correct?
Every single one of those attributes works against successful laser cuttery:
- “Severe weather” → waterproof glue
- The CDX rating: “D is the lowest rating that denotes a lower level of quality”
- “Pressure treated” means it’s saturated with pesticides / preservatives
- “Yellow Pine” → plenty of gooey resinous sap
- “Sheathing” → gnarly surface texture
So, while it may be possible to cut / engrave that stuff, neither your laser nor your lungs will thank you afterward. 
If you must make signs from it, a CNC router seems a better tool for the job.
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