I have a dual head laser (one metal cutting 130w and one for engraving light cutting 80w) these are paired with a ruida 6332m controller. The software connects to the machine and I can control the movement x, y, and z with no issues. However when I go to run a file the laser will not fire. If I move over to rdworks the same file works fine.
In lightburn do you have your machine setting under vendor set to tube. If not start there. If so make sure in your cut layers windows that laser 1 or 2 is enabled.