Things to try:
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Make sure your USB ports aren’t allowed to go to sleep. https://www.windowscentral.com/how-prevent-windows-10-turning-usb-devices
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Try installing the latest FTDI driver (used by Ruida for USB comms): https://www.ftdichip.com/Drivers/VCP.htm
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Try changing the connection mode from Serial/USB to Packet/USB in the device settings. (Click the Devices button, select your laser and click Edit, go from there). Some systems prefer one over the other, for no reason I can figure out.
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You said on your post “through the back of the machine” - How long is the USB cable, and does it have ferrite chokes on it? (the metal rings around it) USB cables aren’t supposed to be very long, so if it’s more than 15 feet you could have signal interference.