It sounds like something got corrupted - when you installed LightBurn, did you install the ftdi drivers on the last step of the installer? If not, I’d advise you re-run the installer and select ‘install drivers’ to reinstall all of those as well.
Lastly, it may be a good idea to reinstall the runtime drivers, as per this post: Lightburn doesn't open (LightBurn 1.7.x -- After Windows Update)