You say the size is 45mm. If my numbers are right, that means you’re trying to produce about 1100 dots per inch. (2032 pixels / 45mm = 45.15 dots per mm, x 25.4 = 1100ish) There is no way your laser’s beam spot is that small - you might get 500 DPI, but even that is optimistic. That’s the biggest problem.
The other is that a Mana SE is an 8 bit processor running at 16MHz, and has a limit to how fast it can process GCode. At a peak density of 45 GCode instructions per millimeter, if you were trying to run this at 16.6mm/sec, that would be 750 GCode instructions per second. A Mana SE can probably do about 500 or a little better, so you’re in the right neighborhood there, but the DPI is so high that it’s going to take forever to get through this, and unless you drop the DPI of the original you won’t be able to process it any faster.