It turns out that I did follow your guide using Box64.
I am running this on a Pi 400 unit (keyboard and Pi all in one)
I did have some issues with getting the right libraries, as many of them were just not available that I could find, so I run mine with the BOX64_ALLOWMISSINGLIBS=1 box64 ./LightBurn command. Other than this issue with the lines in fills, things seem to be working great.
I sync my .lbrn2 files to a NAS I have, then access that NAS from the RPi.