It appears that you have an Workplace Coordinate Offset.
If this is unintentional, open the Console window in LightBurn and type the following:
$#
*RST=#
$#
That should show the before and after and clear the offset.
Feel free to share that in a reply. I’d like to make sure it’s solved.
It seems to happen to Ortur Laser Master 2 Pro S2 less frequently after the Firmware update to OLF187. The firmware update is Highly Recommended: