I have exactly the same issue as above however I am using the serial USB port and Topwisdom controller with my M1 Mac. I have reset and rebooted Lightburn and the laser as advised above.
When I have added the device via “auto detect” or “create manually” it recognises the Topwisdom controller. However, when I send any files to the controller nothing happens - I have selected either the drop down “auto” and “serial usb” when trying to send files to the controller.
I have also deleted the above profiles and reconnected with my windows machine for testing purposes without issue.
I have also tried adding these Mac drivers as described here:
I think I am going to have to purchase a new windows laptop if I can’t get it to run with my M1. Happy to send through pics etc if that helps. Thanks Angie
UPDATE 
I have now managed to get the files to the laser controller via the serial USB connection and my Mac M1 
(macOS Monterey Version12.1). I am running Lightburn version 1.0.06.
I have found that I can only send through very small files such as a basic 2 inch square or two to cut. Any larger files with more detail will not send. When connected to the laser, I used a serial/usb cable with electrical cable chokes on each end.
I also removed any files off the controller memory so that it was clear and also tried sending files via a USB A to USB A cable which did not work.
I think now basically I am having the same issues as mentioned in this post below. It seems that the Lightburn team have been unable to replicate the issue with their Macs used for testing purposes:
Has there been any further updates with this issue or with the beta file that was provided to the original notifier? Any advice would be much appreciated. Hope I have explained myself well enough - not sure of all the technical jargon.
Kind regards
Angie